postdoc position - William Sullivan

POSTDOCTORAL POSITION

Biochemistry, Microbiology, Host-Pathogen Interactions

Indiana University School of Medicine

POSTDOCTORAL POSITION available to investigate host-pathogen interactions during infection with the protozoan parasite Toxoplasma gondii. Related to the malaria parasite, Toxoplasma causes birth defects and life-threatening infection in immunocompromised AIDS or heart transplant patients. The successful candidate will investigate proteome-wide changes in lysine acetylation taking place in the host cell during infection. Lysine acetylation has rapidly emerged as a vital post-translational modification important for protein localization, activity, signaling, and complex formation. Using state of the art genetic and biochemical approaches, the candidate will investigate ways to disrupt lysine acetylation to make the host cell less hospitable for intracellular parasites.

Position requires a Ph.D., expertise in biochemistry & cell biology, and excellent communication skills (speaking and writing English). Experience in host-pathogen interactions and/or bioinformatics is a plus. Submit CV and contact information for three references to Dr. Bill Sullivan (wjsulliv@iupui.edu).

Located in downtown Indianapolis, Indiana University School of Medicine (IUSM) is the second largest medical school in the US and boasts an outstanding intellectual atmosphere and core facilities. IUSM was nationally ranked in the Top 30 Best Places to Work for Postdocs. Our lab is part of a larger intracellular parasitism group at IU that fosters innovation and collaboration. IUSM is an equal opportunity employer. Visit www.sullivanlab.com for more information.

Postdoctoral Position in Breast Cancer Personalize

IDIBELL
 Contacto correo-e:miguelangel.pujana@gmail.com
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Major advances in the understanding of the genetic basis of breast cancer have been made in recent years, but these advances have not led to significant improvements in clinical practice. Moreover, knowledge of the tumor/somatic alterations involved in the disease is disperse, impeding transfer to the clinic and the development of personalized treatments. In this scenario, our group aims at integrating basic and translational research to better define breast cancer subtypes and develop personalized medicine principles.

The Breast Cancer and Systems Biology Group in the Catalan Institute of Oncology (IDIBELL, Barcelona) is interested in finding a highly motivated postdoctoral candidate to apply for a research contract funded by Spanish Association Against Cancer (AECC). The AECC call offers three possibilities, please visit www.aecc.es.

Requirements:
1) PhD degree;
2) postdoctoral experience (at least 4 years for B category)
3) strong publication record in cancer biology

Candidates should send a CV, motivation letter, and 3 contact references no latter than December 31st to Dr. Miquel Àngel Pujana (miguelangel.pujana@gmail.com)

 Información complementaria de la oferta:
Recent publications by the group:
Maxwell et al. (2011). Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer. PLoS Biology Nov;9(11):e1001199.
Martrat et al. (2011). Exploring the link between MORF4L1 and risk of breast cancer. Breast Cancer Research 13(2):R40.
Aguilar et al. (2010). Biological reprogramming in acquired resistance to endocrine treatment of breast cancer. Oncogene 29(45):6071-83.

Postdoc opportunity with Antonio De Maio

I would like to request your help in identifying a potential Post Doctoral candidate to work in my research group studying the mechanism of immune system modulation by stress extracellular vesicles. Please ask candidates to send a copy of their CV directly to me (ademaio@ucsd.edu) or to my assistant Molly Wofford (mwofford@ucsd.edu).

Thank you,

Antonio De Maio 

Postdoctoral Research AECC Call

CIC bioGUNE
 Contacto correo-e:mlmartinez@cicbiogune.es
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The laboratory of Dr. Maria Luz Martinez Chantar at CIC bioGUNE is searching for a Postdoctoral candidate to apply for the AECC Call (Ayudas a investigadores postdoctorales Modalidad A
.
The project will be focused in the Identification of New molecular mechanism implicated in the development and progression of Hepatocelullar Carcinoma. Role of Neddylation.
Candidates must comply with the call requirements. Previous knowledge in liver research will be greatly appreciated.
Interested applicants should e-mail to
mlmartinez@cicbiogune.es including the following information:
1. A cover letter
2. Your CV
3. Names (including e-mail address) of at least two referees

Información complementaria de la oferta:
The laboratory of Dr. Maria Luz Martinez Chantar at CIC bioGUNE is searching for a Postdoctoral candidate to apply for the AECC Call (Ayudas a investigadores postdoctorales Modalidad A
.
The project will be focused in the Identification of New molecular mechanism implicated in the development and progression of Hepatocelullar Carcinoma. Role of Neddylation.
Candidates must comply with the call requirements. Previous knowledge in liver research will be greatly appreciated.
Interested applicants should e-mail to
mlmartinez@cicbiogune.es including the following information:
1. A cover letter
2. Your CV
3. Names (including e-mail address) of at least two referees

POSTDOCTORAL POSITION IN MOLECULAR PARASITOLOGY

Indiana University School of Medicine

Multiyear post-doctoral position available to investigate the role of autophagy and a DNA repair enzyme in drug sensitivity in the protozoan parasite Toxoplasma gondii. Related to the malaria parasite, Toxoplasma causes serious disease in immuno-compromised (AIDS) patients and during pregnancy. We have shown that disruption of a mitochondrial MutS homolog results in multi-drug resistance and that this protein is part of an inducible death pathway that includes cell cycle arrest and autophagy. Potential projects include molecular and biochemical analyses of mitochondrial function in the resistant mutant, characterization of signaling event in the MutS dependent death pathway and investigation of autophagy as a drug induced death pathway.

Position requires a Ph.D., expertise in biochemistry, molecular and cellular biology, and excellent communication skills (speaking and writing English). Experience in molecular parasitology, DNA damage, autophagy, or mitochondrial function is a plus. Submit cover letter, CV, and contact information for three references to Dr. Gustavo Arrizabalaga (garrizab@iupui.edu).

Located in downtown Indianapolis, Indiana University School of Medicine (IUSM) is the second largest medical school in the US and boasts an outstanding intellectual atmosphere and core facilities. IUSM was nationally ranked in the Top 30 Best Places to Work for Postdocs. Our lab is part of a large intracellular parasitism group at IU that fosters innovation and collaboration. IUSM is an equal opportunity employer.

Postdoctoral position in biomedicine

IDIBAPS Barcelona
 Contacto correo-e:mercefernandez@ub.edu
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Postdoctoral Positions in biomedicine: Role of angiogenesis in liver disease
http://www.idibaps.org/biotrack/research-lines/pd33.html

BIOTRACK is an IDIBAPS Programme co-funded by 7PM - European Commission. With this programme, IDIBAPS creates new positions and helps researchers in their further development and expertise.
IDIBAPS wants to recruit excellent young researchers with PhD who have acquired experience in other countries different than Spain. They should have a good track record in scientific publications.
We offer excellent economic conditions and highly motivating and dynamic scientific working environment.

To apply:
It is mandatory to apply through the programme’s website:  http://www.idibaps.org/biotrack/
Each candidate should accomplish the eligibility criteria and present the documentation required (Curriculum vitae, cover letter, recommendation letter/s and scientific abstract based on the framework of a research line from the centre).
Deadline: January 31st 2013

Incentives:
3-year contract
Salary: 38.000€ plus housing facilities
Other incentives

Información complementaria de la oferta:
Employer:
IDIBAPS is a public research recognized worldwide located in Barcelona, Spain. Translational research on biomedicine is the main activity of the institution. See more in www.idibaps.org.

RAMON Y CAJAL CONTRACT

Fundación IMDEA Alimentación
 Contacto correo-e:francesco.visioli@imdea.org
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IMDEA-Alimentacion Institute (Madrid) is looking for a Ramón y Cajal candidate (for further information BOE de 24 de octubre de 2012 (nº 256, págs. 75232-75290). The ideal candidate has experience in molecular biology as applied to the study of micronutrients. Ability to carry out independent research and attract extra-mural funds is a must.
Address candidatures to Francesco Visioli, PhD at francesco.visioli@imdea.org, before Nov 22 2012.

Información complementaria de la oferta:
The IMDEA Food is a research center focused on food, nutrition and health. The main objective of Food IMDEA is to initiate and coordinate research excellence in this area of knowledge, using a multidisciplinary approach and collaboration with academia and industry, focusing on approaches that can lead to a benefit of society.
It main objective is the implementation of research activities, technological development and innovation in the area of nutrition, food and health.

postdoctoral contract

Instituto Cajal
 Contacto correo-e:gonzalo.polavieja@cajal.csic.es
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We are looking for a motivated physicist or biologist interested in decision-making in groups of zebrafish. We have funding for 1 year with the prospect of applying for additional funding in competitive JdC or RyC positions. Interested candidates, please send CV and the names of two references to gonzalo.polavieja@cajal.csic.es


Información complementaria de la oferta:
See additional info at www.neural-cricuirs.org

Búsqueda de candidatos posdoctorales

Instituto IMDEA Alimentación
 Contacto correo-e: arantxa.rodriguez@imdea.org
 Se ofrece posibilidad de solicitar un contrato Juan de la Cierva (posdoctoral, 3 años) de la última convocatoria (BOE Núm. 256, 24 de octubre de 2012) en un grupo de investigación centrado en Alimentación y Salud - área de cardiovascular.
Se busca doctor en biología, farmacia, medicina, bioquímica, biotecnología, y otras relacionadas con el campo de la salud obtenido a partir de 2008, con un curriculum competitivo con publicaciones preferentemente como primer autor.

Requisitos:
1. Haber obtenido el doctorado a partir de septiembre de 2008.
2. Experiencia en cultivos celulares y biología molecular.
3. Se valorará estancias en el extranjero.

Los candidatos interesados deben enviar una carta de presentación y un curriculum en formato normalizado antes del 18 de noviembre 2012 a:
Dra. Arantxa Rodríguez Casado (arantxa.rodriguez@imdea.org), Instituto IMDEA Alimentación

Información complementaria de la oferta:
IMDEA ALIMENTACIÓN (Instituto Madrileño de Estudios Avanzados en Alimentación) es un nuevo Centro de Excelencia en Investigación Alimentaria creado por la Comunidad de Madrid en coordinación con universidades, centros de investigación y empresas. Constituida como Fundación sin ánimo de lucro en el marco del IV PRICIT, su estructura y naturaleza jurídica están orientadas a ayudar a superar la distancia existente entre la investigación y la sociedad. IMDEA ALIMENTACIÓN pertenece a la Red de Institutos Madrileños de Estudios Avanzados promovida por la Comunidad de Madrid con el objeto de desarrollar investigación útil para la sociedad y de excelencia científica internacional.
IMDEA Alimentación tiene como objetivo la realización de una Investigación en Ciencia y Tecnología de Alimentos de Excelencia, Transferible y Explotable, con el fin de contribuir a la generación de conocimiento científico de excelencia, estar al servicio del bienestar social y calidad de vida, elevar la competitividad de la industria alimentaria y contribuir a la formación avanzada y continuada de los profesionales del ámbito alimentario. Más información en www.alimentacion.imdea.org

Contrato Post-doctoral Juan de la Cierva

Instituto de Biología y Genética Molecular (IBGM), CSIC
 Contacto correo-e: carlosv@ibgm.uva.es

Se ofrece contrato post-doctoral con cargo al programa Juan de la Cierva para trabajar en el grupo de investigación de del Dr. Carlos Villalobos (CARLOSV@IBGM.UVA.ES; Calcio Mitocondrial en Quimioprevención y Neuroprotección) en el Instituto de Biología y Genética Molecular (IBGM), centro mixto de la Universidad de Valladolid y el CSIC en Valladolid.

DURACION del contrato: 3 años

TEMATICA: Papel de los canales de calcio y la mitocondria en el control de la proliferación y muerte celulares;  Fisiopatología del calcio intracelular en el cáncer y las enfermedades cardiovasculares y neurodegenerativas (Enfermedad de Alzheimer)

REQUISITOS: Título de doctor reciente y publicaciones científicas en el área de la Fisiología Celular y Molecular.

SE OFRECE incorporación a un grupo de investigación experto en señales de calcio formado por 8 investigadores y formación en técnicas de imagen de fluorescencia y bioluminiscencia así como electrofisiología planar, dentro de un centro de investigación formado por 150 investigadores.

Se valorará especialmente los conocimientos y experiencia previa en el estudio de la señal de calcio así como en técnicas de Fisiología Celular y Molecular.

CONTACTO: Los interesados/as deben ponerse en contacto INMEDIATAMENTE (el plazo acaba el 20 de noviembre) con el Dr. Carlos Villalobos a través del correo electrónico: carlosv@ibgm.uva.es.

Información complementaria de la oferta:
Por favor, adjúntese un breve CV con indicación expresa de la experiencia profesional, listado de publicaciones científicas y fecha de obtención de la Tesis Doctoral.

El Dr. Carlos Villalobos es Investigador Científico del CSIC en el IBGM de Valladolid (Villalobos C and Calcium en PUBMED).

Constrato postdoctoral Juan de la Cierva

Instituto de Salud Carlos III
 Contacto correo-e:mamblar@isciii.es

Searching for Posdoctoral
candidates
(Juan de la Cierva 2012 Call)

Group: Molecular Biology of Pneumococcus
Supervisor of the position: Dr. Mónica Amblar Esteban
Research interest of the group: Our group is interested in the role of small non-coding RNAs as modulators of virulence in Streptococcus pneumoniae.
Pneumococcus is the main etiological agent of community-acquired pneumonia and a major cause of mortality and morbidity among children and the elderly. Understanding how bacterial pathogens respond to dynamic environments is a central aspect in microbial pathogenesis and there are increasing evidences implicating small RNAs as vital regulators of adaptation and virulence.
We have identified a big repertoire of small non-coding RNAs that are expressed in S. pneumoniae using next-generation sequencing. Now, our main goal is to elucidate how these small RNAs modulate gene expression in pneumococcus to adapt its metabolic needs during infection. The work will involve in vitro growing of bacterial cells under different stress conditions, construction of knock out strains, genomic translational and transcriptional fusions, analysis of gene expression through qRT-PCR and Northern blot, analysis of virulence, etc.
Requirements:
1.      PhD obtained on September 1, 2008 or later.
2.      At least 2 first author papers in international journals.
3.      Previous experience in bacterial manipulations and biochemistry and molecular biology techniques.

Interested candidates should send a cover letter and CV
(please include contact information for 2 referees)
before November 19, 2012 to:
Mónica Amblar Esteban: mamblar@isciii.es
Centro Nacional de Microbiología, Instituto de Salud Carlos III

Información complementaria de la oferta:
Interested candidates should send a cover letter and CV
(please include contact information for 2 referees)
before November 19, 2012 to:
Mónica Amblar Esteban: mamblar@isciii.es
Centro Nacional de Microbiología, Instituto de Salud Carlos III

Candidatos contrato Juan de la Cierva

Hospital Valle Hebron/Institut de Recerca Vall de hebron
 Contacto correo-e:joan.sayos@vhir.org
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El Grupo de Inmunobiología del Institut de Recerca Vall  d'Hebron de Barcelona busca candidatos para solicitar un CONTRATO POST-DOCTORAL de 3 años de duración con cargo al subprograma Juan de la Cierva del MICINN  (MICINN-JDC).

http://www.idi.mineco.gob.es/portal/site/MICINN/

El candidato se incorporará a nuestro Grupo para trabajar en un proyecto financiado por el FIS :“CD300 immunoreceptors;  Functional characterization and implication in inflammatory demyelinating  diseases.”

Perfil del candidato:

- Doctor en Bioquímica, Biologia, Medicina o similar.
- Un mínimo de tres publicacions del primer quartil (ISI)
- Dedicación a tiempos completo.
- Se valorará experiencia en Neurociencias, Inmunologia i/o en modelos animales
(ratones o rata)

Las personas interesades enviar CV a:

Dr. Joan Sayós (joan.sayos@vhir.org)
Tel: 93 4893000 ext 3753

Información complementaria de la oferta:
Información sobre el proyecto de Investigación

The CD300family of immunoreceptors is composed by six members, CD300a/IRP60, CD300b/IREM3, CD300c/CMRF35, CD300d, CD300e/IREM2 and CD300f/IREM1. All of them share an extracellular region comprising a single Ig-like domain and, with the exception of CD300a, a myeloid linage restricted pattern of expression. In addition to the expression on myeloid cells, CD300a is found in some subsets of T, B and NK cells. The Immunobiology group is focused on the study of the structure and function of the CD300 family of immune receptors, as well as in their involvement in different human pathologies.

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (SNS) that affects more than 2.5 million individuals worldwide. The first symptoms appear between 20 and 30 years and is the main neurological disease in young adults, with higher incidence in women. Although the mechanisms underlying MS pathogenesis are still unclear, it is well known that patients' blood-brain barrier allows the passage of macrophages and lymphocytes to the NHS thereby initiating an inflammatory process. This inflammatory response includes activation of microglial cells and autoimmune attack against white matter oligodendrocytes. We propose, based on previous experimental data, the study of the role of the CD300f in the pathophysiology of this disease. First, we are working in the identification of the physiological ligand for this receptor, that we know is expressed by certain cells in the SNS. Secondly, the analysis of the role of soluble forms of CD300f in the
 development of the disease by studying their expression in fluid samples of multiple sclerosis patients. Since activation of microglia and macrophages is critical in the development and expansion of MS lesions, the study of the mechanisms that regulate the activation of these cells may be of vital importance in the development of new therapeutic agents for the treatment of this disease.

Publicaciones recientes del Grupo de Investigación sobre el tema

Comas-Casellas E, Martínez-Barriocanal A, Ejarque-Ortiz, A, Miro, F,  Schwartz S Jr, Martín M, and Sayós J. CD300d is a new member of the CD300 family of receptors that regulates their surface expression. J Biol Chem. 287: 9682-9693. (2012)

Peluffo, H, Alí-Ruiz, D,  Ejarque-Ortíz, A, Heras-Alvarez, V, Comas-Casellas, E, Martínez-Barriocanal, A, Kamaid, A, Alvarez-Errico, D, Negro, ML, Lago, N, Schwartz Jr, S, Villaverde, A and  Sayós, J. Overexpression of the immunoreceptor CD300f has a neuroprotective role in a model of acute brain injury. Brain Pathol. 22:318-328. (2012)

Martínez-Barriocanal A, Comas-Casellas E, Schwartz S Jr, Martín M, and Sayós J. CD300 heterocomplexes, a new and family-restricted mechanism for myeloid cell signaling regulation. J. Biol. Chem. 285:41781-94. (2010).

Postdoctoral position in cancer biology

IDIBELL
 Contacto correo-e:mapujana@iconcologia.net

Postdoctoral position in cancer biology

The Breast Cancer and Systems Biology Group in the Catalan Institute of Oncology (IDIBELL, Barcelona) is interested in finding a highly motivated postdoctoral candidate to apply for a “Juan de la Cierva” contract.

Requirements: 1) Ph.D. degree obtained after Sept 1st 2008; 2) experience in animal experimentation, molecular biology, cell biology, and/or functional genomics; and 3) good publication record.

Candidates should send a CV and references before November 12 to Dr. Miquel Àngel Pujana (miguelangel.pujana@gmail.com)

Información complementaria de la oferta:
Recent publications by the group:
Maxwell et al. (2011). Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer. PLoS Biology Nov;9(11):e1001199.
Martrat et al. (2011). Exploring the link between MORF4L1 and risk of breast cancer. Breast Cancer Research 13(2):R40.
Aguilar et al. (2010). Biological reprogramming in acquired resistance to endocrine treatment of breast cancer. Oncogene 29(45):6071-83.

Postdocs - Sara Borrell

Instituto de Investigaciones Vall d'Hebron, Barcelona, Spain
Contacto correo-e: diego.arango@vhir.org

CONTRATOS POSTDOCTORALES SARA BORRELL

Se busca un candidato/a altamente motivado/a que cumpla los requisitos para solicitar un contrato Saran Borrell (http://www.isciii.es/ISCIII/es/contenidos/fd-investigacion/fd-financiacion/fd-convocatorias-ayudas-accion-estrategica-salud/fd-guias-ayuda/GUIA_AYUDA_SARA_BORRELL_2012.pdf).

REQUISITOS DE LOS CANDIDATOS:

- Doctores españoles o nacionales de alguno de los Estados de la Unión Europea o de un país no comunitario con residencia legal en España en el momento de presentar la solicitud, que hayan obtenido el doctorado posteriormente al 1 de enero de 2009, excepto en los casos debidamente justificados previstos en la convocatoria.

- Buen record de publicaciones en el campo de la oncología molecular.

CARACTERÍSTICAS DE LOS CONTRATOS:

- Un sueldo de unos 27.000 euros brutos anuales.

- El programa incluye una estancia obligatoria de 6 a 9 meses en un centro extranjero.

- Ambiente académico activo y estimulante.

El candidato se incorporaría al Grupo de Oncología Molecular del Instituto de Investigaciones Vall d’Hbrón/CIBBIM (http://www.vhir.org/gr/nanomolecularoncology) previsiblemente a finales del 2012 o principios del 2013. El candidato trabajará en la identificación de marcadores moleculares de pronóstico y respuesta a tratamiento para pacientes con cáncer colorrectal usando un amplio abanico de técnicas en el campo de la biología celular y molecular, con trabajos in vitro, modelos animales y colecciones de muestras clínicas.

Contactar antes del 19 de junio de 2012 con Diego Arango (diego.arango@vhir.org)


Información complementaria de la oferta:
Arango D, Al-Obaidi S, Williams DS, Dopeso H, Mazzolini R, Corner G, Byun DS, Carr AA, Murone C, Tögel L, Zeps N, Aaltonen LA, Iacopetta B, Mariadason JM. Villin expression is frequently lost in poorly differentiated colon cancer. Am J Pathol. 2012 Apr;180(4):1509-2

Mazzolini R, Dopeso H, Mateo-Lozano S, Chang W, Rodrigues P, Bazzocco S, Alazzouzi H, Landolfi S, Hernández-Losa J, Andretta E, Alhopuro P, Espín E, Armengol M, Tabernero J, Ramón Y Cajal S, Kloor M, Gebert J, Mariadason JM, Schwartz S Jr, Aaltonen LA, Mooseker MS, Arango D. Brush border Myosin Ia has tumor suppressor activity in the intestine. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1530-5. Epub 2012 Jan 18

Dopeso H, Mateo-Lozano S, Elez E, Landolfi S, Ramos Pascual FJ, Hernández-Losa J, Mazzolini R, Rodrigues P, Bazzocco S, Carreras MJ, Espín E, Armengol M, Wilson AJ, Mariadason JM, Ramon Y Cajal S, Tabernero J, Schwartz S Jr, Arango D. Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment. Clinical Cancer Research. 2010 Apr 15;16(8):2375-82.

Alhopuro P, Phichith D, Tuupanen S, Sammalkorpi H, Nybondas M, Saharinen J, Robinson JP, Yang Z, Chen LQ, Orntoft T, Mecklin JP, Järvinen H, Eng C, Moeslein G, Shibata D, Houlston RS, Lucassen A, Tomlinson IPM, Launonen V, Ristimäki A, Arango D, Karhu A, Sweeney HL, and Aaltonen LA. Unregulated smooth muscle myosin in human intestinal neoplasia. Proceedings of the National Academy of Sciences, 2008; 105(14):5513-8. Epub 2008 Apr 7.

Davalos v, Dopeso H, Velho S, Monteiro Ferreira A, Cirnes L, Díaz-Chico N, Bilbao C, Ramírez R, Rodríguez G, Falcón O, León L, Niessen R, Keller G, Dallenbach-Hellweg G, Espín E, Armengol M, Perucho M, Imai K, Yamamoto H, Gebert JF, Díaz-Chico JC, Hofstra RM, Woerner SM, Seruca R, Schwartz Jr. S, Arango D. High EPHB2 mutation rate in gastric but not endometrial tumors with microsatellite instability. Oncogene, 2007;26(2):308-11

Davalos V, Dopeso H, Castaño J, Wilson AJ, Vilardell F, Romero-Gimenez J, Espín E, Armengol M, Capella G, Mariadason JM, Aaltonen LA, Schwartz Jr. S, Arango D. EPHB4 and survival of colorectal cancer patients. Cancer Research, 2006; 66(18):            8943-8948    

Ropero S, Fraga MF, Ballestar E, Hamelin R, Yamamoto H, Arango D, Aaltonen LA, Schwartz S Jr, Esteller M. A truncating mutation of HDAC2 in human cancers confer resistance to histone deacetylase inhibition. Nature Genetics, 2006;38(5):566-9

Paroder V, Spencer SR, Paroder M, Arango D, Schwartz Jr S, Mariadason JM, Augenlicht LH, Eskandari S, and Carrasco N. Na+/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: Molecular characterization of SMCT. Proceedings of the National Academy of Sciences, 2006 May 9;103(19):7270-5

Alazzouzi H, Davalos V, Kokko A, Domingo E, Woerner SM, Wilson AJ, Konrad L, Laiho P, Espín E, Armengol M, Imai K, Yamamoto H, Mariadason JM, Gebert JF, Aaltonen LA, Schwartz S Jr., Arango D. Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors. Cancer Research, 2005; 65(22):10170-3

Postdoctoral Position in Neuroscience

IDIBAPS
 Contacto correo-e:vfernand@clinic.ub.es
 We seek for a motivated postdoc that is willing to apply for an AGAUR “Beatriu Pinós” (Generalitat de Catalunya) contract in our Systems Neuroscience research group (Sanchez-Vives lab).

The candidate should have training in neuroscience and electrophysiology. Applicants must have at least 2 years of postdoctoral training abroad (Spain not included) and have first-authored publications. The research group is  at the  Institut d’Investigacions Biomediques August Pi I Sunyer (IDIBAPS). The Institute offers strong interactive environment and various excellent opportunities for collaborative research exist. Interested applicants are encouraged to apply with an email containing your curriculum vitae, and names and contact information of two references to Vanessa Fernandez via email: vfernand@clinic.ub.es

Postgraduate/postdoctoral position

A postgraduate/postdoctoral position is available immediately to join a basic science/translational research laboratory in the Department of Medicine in the University of Texas Health Science Center in San Antonio, Texas, United States of America. The laboratory is well established and headed by Dr. Sunil K. Ahuja, Professor of Medicine and Microbiology. We use a multi-disciplinary approach including immunological, genetic, epigenetic, bioinformatic, and genomic studies to understand host resistance to infectious/non-infectious diseases and mechanisms that lead to altered immune status. The laboratory is equipped with state-of-the art facilities for genome wide association studies and Next Generation Sequencing (ChIP-Seq and RNA-Seq).
Highly motivated candidates with a Master's or a doctoral degree with a strong research background in molecular and cellular biology, biochemistry, and genetics/genomics are particularly encouraged to apply. Experience in bioinformatics/computational biology is highly desirable. Strong analytical and communication
skills with a publication record would be favorably considered.
Interested candidates should send their CV, a letter of interest outlining experience and research goals, and the names of 3 references to ahujas@uthscsa.edu.

Contact in Argentina: Dra. Andrea Mangano (amangano@garrahan.gov.ar)

Postdoctoral positions in Molecular and Cellular Neuroscience

Postdoctoral positions in Molecular and Cellular Neuroscience

Applications are invited for two postdoctoral positions at the Institute of Experimental Medicine in Budapest, Hungary. The two positions (funded by the European Research Council and by The Wellcome Trust) are available immediately, can be granted for up to 4 years and offer a very competitive salary for the cost of living in Eastern Europe.

The postdoctoral fellows will join an international team of researchers led by Prof. István Katona. The lab is focusing on the identification and functional characterization of new endocannabinoid-related signaling pathways in the brain. The prospective fellows will have the unique opportunity to access multidisciplinary techniques including super-resolution microscopy, live cell imaging, high-resolution electron microscopy, patch-clamp electrophysiology and biochemistry/molecular biology.

Detailed information on the conceptual and methodological background of the team can be found at www.katonalab.hu or in the following articles: Nature Medicine 14:923-930; Science 325:760-4; Science 316:1212-16; Neuron 56:33-42; Journal of Neuroscience 28:2976-90; Journal of Neuroscience 28:1058-63; Journal of Neuroscience 26:5628-37; European Journal of Neuroscience 29:1964-78.

The Institute of Experimental Medicine is a highly collaborative and stimulating research environment led by the Brain Prize winner Prof. Tamás Freund. It holds a Center of Excellence title from the European Union and is widely regarded as a leading Neuroscience center in Europe (e.g. currently six Wellcome Trust Senior Fellows have research groups at the IEM). The Institute is well equipped with core facilities, such as the SPF transgenic animal facility, several electron microscopes, N-STORM super-resolution microscope and other state-of-the-art confocal and physiological microscopes at the new NIKON Microscopy Center. It is conveniently located in the center of Budapest, in close vicinity of the Semmelweis Medical University and major cultural hotspots. Budapest is considered as one of the most vibrant European cities, where a Western lifestyle is combined with a special Eastern flavour.

Successful candidates will hold a PhD and / or MD and have an excellent track record in either: 1) electrophysiology, including patch-clamp recording from neurons in brain slices; 2) molecular neurobiology, including work with tissue cultures, immunocytochemistry, confocal microscopy. Outstanding candidates with expertise in other areas may also be considered.

To apply, please send a CV, a short letter describing your motivation and research experience as well as contact information for two references. For application or informal inquiries please contact Prof. István Katona (katona@koki.hu).