8 March 2012

Open post-doctoral position on HIV Immunopathogenesis in Paris

A post-doctoral position is available for two years to work on a translational research program focusing on immune correlates of disease progression in HIV infection. This program is funded by the ANRS in collaboration with Sidaction and INSERM.

The successful applicant will join the team "HIV pathogenesis and immunosenescence" led by Dr Victor Appay within the INSERM unit “Immunity and Infection” based at the Pitié-Salpétrière Hospital (in Paris).

A central research topic of our team is on the reasons behind the onset of immunodeficiency in HIV infection. In this context, we are interested in the concept of T lymphocyte exhaustion and its relevance in HIV pathogenesis. The successful applicant will study immune characteristics related to T-cell development and renewal, activation and inflammation in HIV infected individuals. She/he will study in particular the impact of vitamin D deficit in the establishment of elevated inflammation and/or the decline of immune competence in humans. The tasks will include: to develop new tools in cellular immunology, to generate ex vivo (patients) and in vitro (models) data, to analyse and communicate results, and to prepare manuscript for publication.

The applicant must have a PhD with research experience in the fields of immunology/immunopathology/infectious diseases, be strongly motivated by the study of virus/host interactions, and have very good skills in communicating in English (oral and writing). Skills in cellular immunology and flow cytometry are required as well as a strong background in fundamental immunology. Experience in the field of infectious diseases and/or anti-viral immunity, self-motivation, ability to work independently and in collaboration, and experience in training students are additional assets. The successful applicant is expected to join the team within 4-5 months.

Applications including a curriculum vitae and a cover letter detailing your skills and motivations should be sent by email to: victor.appay@upmc.fr

Antonio José Alberdi, Ph.D.
Plate-Forme Génomique IUH-Hopital Saint-Louis
Institut Universitaire d'Hématologie
Hôpital Saint Louis
Paris 75010
Tel:                         +33 1 57 27 67 92            
e-mail: aalberdy@hotmail.com

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