POSTDOCTORAL RESEARCH POSITION
IN BEHAVIORAL NEUROSCIENCE
A Postdoctoral
position is available immediately (APRIL 1 2011; start date is flexible) in
the laboratory of Dr. Victoria Risbrough, Assistant Professor of Psychiatry, University
of California, San Diego.
Research in the
laboratory focuses on cross-species translational research with relevance to
neuro-psychiatric disorders. Current topics of interest in the laboratory are
mechanisms of stress and their contribution to development of neuropsychiatric
disorders such PTSD, schizophrenia and bi-polar disorder. Specifically we aim
to 1) develop animal models of these disorders, 2) understand the neurobiology
contributing toward these deficits using genetic and pharmacological
techniques, and 3) develop complementary tasks of stress responding for
pharmacological challenge studies in humans. Developing these models include
both developing paradigms with cross-species translational validity and
manipulating the animal via pharmacologic, genetic, or developmental means.
The position
available is to work on a recently funded R01 award examining the effects of
pharmacological and genetic manipulations of the corticotropin releasing factor
(CRF) system in the development of enduring anxiety using a feline predator
stress model of PTSD in mice. This
position involves use of transgenic mouse model (tissue-specific conditional
overexpression of CRF) to examine critical developmental windows of CRF
contribution to trait stress responding across the lifetime. This position also involves using stereotaxic
techniques combined with pharmacological and viral tools to identify neural
circuits and systems underlying maladaptive responses after trauma exposure in
adult mice. There will also be
opportunity for the candidate to develop skills in other areas, including
development of human models of stress responding.
The
candidate should hold a Ph.D., have a strong conceptual and experimental
background in neuroscience, experience in general neuroscience techniques (e.g.
in situ hybridization,
immunohistochemistry), as well as be proactive, independent, hardworking,
productive, and enjoy working as part of a team. The most competitive
candidates will be those with at least one first-author publication in the
field and should be committed to eventually becoming self-funded via grant
applications.
Please send your CV, a brief statement of current and future
research interests, and three references to:
Victoria
Risbrough, Ph.D. vrisbrough@ucsd.edu
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