Postdoctoral position
High spatiotemporal Resolution microscopy to follow mRNAs ribonucleoparticles, from
their biogenesis to their nuclear export in living Yeast cells.
A 2-years postdoctoral position funded by the Labex WHO AM I is available in the team of C.
Dargemont at the Institut Jacques Monod (CNRS/Université Paris Diderot). This will be a
collaborative project
with teams of P. Hersen (Matiere et Systemes complexes, CNRS/
Université Paris Diderot) and J. Salamero/C. Kervrann ( Serpico-PICT IBiSA; Institut CurieINRIA).
Start date is between September and December 2012.
The interdisciplinary project proposes to combine the development of innovative superresolution
methods, bioimage informatics approaches and genetic engineering in order to image
the export-competent mRNP formation in yeast cells with time regimes compatible with kinetics
to be observed and space resolution adapted to the limited size of the yeast nucleus.
The candidate will beneficiate from the combined expertise of Salamero’s, Kervrann’s,
Dargemont’s and Hersen’s teams in bioimaging, bioimage informatics, mRNP biogenesis and
nuclear export, and microfluidics applied to yeast biology.
The ideal candidate would have proven an in deep knowledge in photonic microscopy (optics,
particle tracking, signal treatment) and eventually in biophysics but will be localized in a biology
team.
Interested candidates should send a motivation letter, a CV, a list of publications and three
reference letters to C. Dargemont (dargemont.catherine@ijm.univ-
References
-Dokudovskaya S, Waharte F, Schlessinger A, Pieper U, Devos DP, Cristea IM, Williams R, Salamero J,
Chait BT, Sali A, Field MC, Rout MP, Dargemont C. (2011) Mol. Cell Proteomics.
10(6):M110.006478.
-Vitaliano-Prunier, A*., Babour A.*, Hérissant, L.*, Apponi, L., Margaritis, T., Holstege, FCP, Corbett,
AH, Gwizdek, C.* and Dargemont, C.* (2012) Mol Cell. 1: 132-139.
-Hayakawa, A., Babour, A., Sengmanivong, L. and Dargemont, C. (2012) J. Cell Biol. 1:19-27.
-Hersen P, McClean MN, Mahadevan L, and Ramanathan S. (2008) Signal Processing by the HOG MAP
Kinase
pathway, PNAS, 105, 7165-7170.
No comments:
Post a Comment