A Bio-Protection Research Centre funded PhD studentship is available to
pursue PhD research on signalling in a fungal endophyte-grass symbiotic
interaction. The project is based in the Institute of Molecular
BioSciences (IMBS), Massey University, Palmerston North and will be
jointly supervised by Professor Barry Scott and Dr Carla Eaton. The
research is collaborative with Ass Prof Daigo Takemoto, Nagoya
University, Japan.
Epichloë festucae is a biotrophic fungus that forms symbiotic
associations with temperate grasses of the Festuca and Lolium species.
The association between E. festucae and L. perenne (perennial ryegrass)
is an ideal experimental system to study this fungal-plant symbiotic
interaction. Integral to the establishment and maintenance of this
association is mutual communication between the endophyte and host
partner.
A key signal transduction pathway for regulating various cellular
processes during development and pathogenesis in filamentous fungi, and
that acts upstream of MAP kinase pathways, involves the heterotrimeric G
proteins. These complexes have universal roles as mediators for
transferring external cellular signals from G-protein coupled receptors
(GPCR) to downstream effectors in eukaryotes.
The aim of this research is to test whether any of the G-protein coupled
receptors (GPCR) found in E. festucae are essential for the symbiosis,
and to dissect their role in downstream signalling through the
heterotrimeric G proteins. The results of this work will provide
fundamental insights into understanding the molecular basis for why
there is such a fine balance between whether a fungal-plant interaction
will be mutualistic or pathogenic.
We are looking for a highly motivated student with a keen interest in
fungal-plant symbiotic interactions with a BSc(Hons) or MSc degree in
Genetics, Biochemistry, Microbiology or a related discipline. Experience
in fungal genetics and biology would be an advantage.
The studentship provides for an annual stipend of $28,000 plus domestic fees for a period of 3 years.
Applications, including a CV and full contact details of two referees
should be sent to Professor Barry Scott, Institute of Molecular
BioSciences, Massey University by 1 December 2011. Email: d.b.scott@massey.ac.nz
Barry Scott
d.b.scott@massey.ac.nz
Massey University
Palmerston North, New Zealand
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