EPSRC PhD Studentship starting October 2011: Developing the microdroplet platform for interdisciplinary science.
Supervisors: Professor Chris Abell (Chemistry), Professor Alison Smith (Plant Sciences)
Project outline:This is a joint project with Professor
Chris Abell's group in Chemistry and Professor Alison Smith's group in
Plant Sciences, building on our initial work to apply microdroplet
technology to cell biology. Microdroplets are typically 20-100 micron
water droplets carried through a microfluidic device in an oil stream
[1]. The Microdroplet group have developed devices capable of trapping
cells in droplets, where they can be grown, analysed and sorted at rates
of up to 10 kHz. Optical detection allows the number of cells to be
monitored, whilst fluorescence measurements can be used to quantify
chemical composition. The project will develop these specifically
formatted experimental platforms to carry out high-throughput screening.
Suitable candidates could have background in chemistry, chemical
engineering, biochemistry or plant/algal biology, but must be prepared
to work at the interface between physical sciences and biology.
References
1. Theberge et al (2010) Microdroplets in Microfluidics: An Evolving
Platform for Discoveries in Chemistry and Biology. Angew. Chem. Int. Ed.
49: 5846-5868.Applications are welcomed from UK and EU students.
Overseas students are not eligible for this Studentship.
The minimum qualification for Ph.D. studies is a Class 2.1 Honours Bachelors Degree.
Please email Professor Chris Abell (ca26@cam.ac.uk) as soon as possible (and no later than 15 June) if you are interested in this project.
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