Postdoctoral Fellow/Senior Scientist at the European School of Chemistry

Postdoctoral Fellow/Senior Scientist at the European School of  Chemistry, Polymers and Materials (ECPM), Strasbourg France, in the research unit UMR7509: a post-doctoral position for a chemist is available for 18 months from now (as soon as possible) or no later than March 1, 2011 (sooner is preferred).

The salary will be paid by the French Centre National de la Recherche   Scientifique (CNRS) in Strasbourg. The position is allocated in a  project on the optimization of an antiparasitic drug-candidate.

The project will focus on "Identification of the binding site of  antimalarial agents acting as subversive substrates of glutathione  reductases".

Successful applicants should have a strong background in structural   enzymology in the presence of inhibitors (kinetic parameters) and  advanced enzymology under oxygen-free conditions, mechanistic   studies. Experience with photoaffinity labelling of proteins in the  presence of photoreactive reagents, or with mass spectrometry  analysis of alkylated enzymes, or cristallogenesis of enzymes in the   presence of ligands, would be much appreciated. Solid communication skills in English (written, oral) and a strong publication record in
internationally circulated, peer-reviewed journals are mandatory.  Only self-motivated and energetic candidates are encouraged to  apply; please send a letter of interest, two letters of recommendation,   CV containing the list of diploms and experiences, and publication list  to Elisabeth Davioud-Charvet. Only complete, electronic applications  in pdf format (elisabeth.davioud@unistra.fr) will be considered. The   review of applications will start from now, and continue until the  position is filled. The co-supervisor of this project will be Alain van  Dorsselaer, expert in analytical chemistry and mass spectrometry in   our institute, Strasbourg.

Applications have to be sent to: Elisabeth Davioud-Charvet, European  School of Chemistry, Polymers and Materials (ECPM), Chimie  moléculaire, UMR CNRS 7509, 25, rue Becquerel, F-67087   Strasbourg, France Tel: +33 3 68 85 26 20 ; Fax.: +33 (0)3 68 85 27  42 

URL: http://www-ecpm.u-strasbg.fr/umr7509/labo_davioudcharvet/